Crohn's Disease Activity Index

Composite activity index from a 7-day symptom diary.

Crohn'sClinicalValidated score

Clinical indication

Symptomatic disease activity in adult Crohn's disease, over the preceding seven days. Historically the primary endpoint in Crohn's trials; in practice it is used mainly where a standardised, comparable activity measure is needed.

What is scored

Composite activity index from a 7-day symptom diary.

Any item left blank stops the score being calculated — an incomplete form never reports as remission.

Interpretation

< 150Clinical Remission
150 - 219Mildly Active
220 - 450Moderately Active
> 450Severely Active

Bands as implemented in IBD Care. A band is a description of the score, not an instruction.

Limitations

Requires a seven-day patient diary, so it cannot be completed at a single visit. It correlates poorly with endoscopic activity: a patient can sit below 150 with ulcerated mucosa, and the general-wellbeing and abdominal-pain items carry enough weight that coexisting irritable bowel symptoms inflate the score. Not validated for isolated perianal disease.

References

Content last reviewed 2026-10-10. References were resolved against PubMed, a service of the US National Library of Medicine, which does not endorse this site.

Use the calculator

Crohn's Disease Activity Index is implemented as an interactive calculator in IBD Care, with its full guidance and scoring bands.

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